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Angioedema
Angioedema is similar to urticaria, but it
involves slightly deeper-seated tissues. Like urticaria is caused by a build
up of fluid leaking from thin-walled blood vessels. It can accompany
urticaria or occur alone.
Angioedema can be an uncomfortable and disfiguring
conditions, and can very occasionally be life-threatening. The condition that causes
the worst risk is called
laryngeal oedema
the name given to angioedema of the
voice box or larynx.
Angioedema is very similar to urticaria, the two
conditions often occur together. Both are caused by an allergy-like response that occurs in
the skin tissues. In urticaria this response causes release of histamine into the
superficial skin layer and this results in the appearance of wheals. The redness that accompanies hives isn’t seen, but the swelling
is very obvious. The swelling generally occurs on the fingers and toes, as well as areas of
the head, neck, face, and, in men, the reproductive organs, and is often described as painful
or burning. In angioedema, the
histamine-releasing response is deeper down, and this results in the characteristic tissue
swellings of the condition. Both conditions may result from allergy. Sometimes the
cause is obvious, sometimes it can take detailed investigation to find, and sometimes no cause
is found even after detailed investigation. The latter condition is called idiopathic
angioedema. Angioedema swellings may occur in the face,
particularly around the lips or eyes and eyelids. In some cases swellings occur in the lips and other parts of the
mouth and throat. The genitals hands and feet are common areas for the
condition. Sometimes the swellings can cause the lips to look like sausages, and the eyelids may be completely
closed. The tongue may be so swollen that you have difficulty speaking. The throat
may close so that breathing is difficult. Thankfully this latter complication, also
known as
laryngeal oedema is much less common than the other forms. For the vast majority of sufferers
angioedema is a nuisance rather than a life- threatening condition.
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